I understand that you want a game about Totos (a fictional creature) and Karen people implemented as a single HTML file with JavaScript, allowing it to be playable on smartphones. If possible, you would like to use emojis.
Here is a simple example of a game using emojis, implemented as an HTML file with JavaScript:
Please note that creating a fully functional 3D game with complex mechanics may not be feasible within the limitations of a single HTML file. However, you can certainly create a more simplified game using JavaScript and basic HTML elements. You may need to use external libraries or frameworks for achieving a 3D effect.