Sure! Here's an example of a single HTML file with JavaScript that implements the game you described:
Sad Emoji Game
Score: 0
This code sets up a basic game where you control a sad emoji character using left and right arrow keys to avoid the snake's venom. The game starts automatically and keeps track of your score. The sad emoji moves left and right on user input, and the snake and venom move towards the emoji. If the venom collides with the emoji, the game ends. You can replace the URLs of the image backgrounds with actual image URLs to use pictograms.