Sure! Here's a simple HTML game implementation of a boss fight using pictograms:
In this game, you control a character represented by a smiley face emoji. The boss, represented by an angry face emoji, shoots green lasers at you and occasionally shoots a blue orb. To deplete the boss' health, you have to hit it with your character or laser shots.
You can move your character by dragging your finger across the screen (assuming smartphone operation) and shoot lasers by tapping on the screen. The boss' health is displayed at the top left corner, and your character's health is displayed at the bottom left corner. If your character's health reaches 0, you lose the game. If the boss' health reaches 0, you win the game.
Please note that the game logic is simplified for the purpose of this implementation. Feel free to enhance and customize it further to fit your desired gameplay.