Sure! Here's an example of a JavaScript game implemented as a single HTML file, using pictograms and incorporating the requested features:
This HTML file contains a game area where a single emoji is displayed. The emoji changes randomly every 0.3 seconds. Every 10 seconds, a "WEIRDNESS INCOMING" message is displayed, followed by the execution of one of four random commands requested. The commands include "PARTY" (background color change), "more emojis" (adding more emoji elements), "why is it raining" (background rain effect), and "different texture" (changing emoji appearance). After another 10 seconds, the weirdness stops and the random emoji change resumes.