Sure, here is an example of a simple Snake game implemented as a single HTML file using JavaScript:
This implementation creates a snake game in a 20x20 grid (400x400 pixels). The snake moves and the player controls its direction using the arrow keys. The goal is to eat the red food items that appear randomly on the board without hitting the boundaries or the snake itself. If the game is over, an alert message will be displayed.
Please note that this is a basic example and can be further enhanced with additional features and improvements based on your specific requirements.