As an AI language model, I can help you create the basic structure for an interactive game in a single HTML file, but I cannot implement the entire game logic as it requires detailed specifications and design. Here's an example of a simple HTML file with JavaScript that you can use as a starting point for your game:
In this example, the game container is defined by the `<div id="game-container">` element, and the game content can be placed inside the `<div id="game-area">`. You can dynamically update the game content using JavaScript based on your game's logic.
Note that this is just a basic template to get you started. You'll need to add your game logic, event handlers, and more to make it a fully functional game. Feel free to modify and expand upon this code to suit your needs.