Sure! Here's an example of a game called "Space Killer and Alien in Space" implemented in a single HTML file using JavaScript:
In the game, there is a spaceship represented by a pictogram and an alien represented by another pictogram. The spaceship can be controlled by touching the screen. The alien moves to a random position on the screen every 2 seconds.
Please note that in the code above, you need to replace the URLs in the `background-image` CSS properties (`emozi_all/background.png` and `emozi_all/spaceship.png`) with the actual URLs of the pictograms you want to use. Also, make sure to have those images available in the same directory as the HTML file.