As an AI text-based model, I can provide you with a basic template and structure for creating a simple fighting game using HTML and JavaScript. However, note that creating a fully functional game similar to Guilty Gear Strive requires extensive development and design skills. Here's a simplified example to get you started:
Simple Fighting Game
This is a simplified template that sets up a basic structure for a two-player fighting game. You'll need to include appropriate styles, images, and animations for the game elements to make it visually appealing and playable.
Please note that developing a fully functional fighting game requires substantial programming and game development expertise. This example serves as a starting point, and it's up to you to enhance it with game mechanics, character movements, attacks, and animations to make it playable and enjoyable on iPadOS or any other platform.