Sure, here's an example of a simple JavaScript game implemented as a single HTML file using pictograms. This game is called "Pokemon Master EX" and it is optimized for smartphone operation.
Pokemon Master EX
In this example, the game consists of a 3x3 grid where each cell represents a Pokemon pictogram. When the player taps on a cell, the corresponding Pokemon pictogram is revealed. The goal of the game could be to match pairs of Pokemon by revealing the pictograms and remembering their positions.
Note that this is a simple implementation and there are many ways to expand and improve the game mechanics, such as adding game logic, score tracking, and win conditions.