Sure! Here's a basic implementation of a tower defense game using JavaScript in a single HTML file:
In this game, the player's goal is to defend their territory by placing towers and stopping enemy icons from reaching the right side of the gameboard. The player can place towers by tapping on the gameboard, and the towers will automatically attack any enemies that come into contact with them. The game runs on a loop, moving enemies towards the right side every 100ms and checking for collisions between towers and enemies. If an enemy reaches the right side, the game is over.