Sure! Here's a simple example of a 2D game implemented as a single HTML file using JavaScript and pictograms for smartphone operation. Please note that this is just a basic example to give you an idea of how it could work:
Please note that this is just a basic framework for a game and you would need to implement the game logic, controls, collisions, and game over conditions based on your specific game requirements. Additionally, you should style and customize the game visuals and pictograms according to your preferences.