Sure! Here's a sample implementation of a simplified version of the Mario game using JavaScript and HTML:
This is a basic implementation of a Mario-like game where you can move left and right using the left and right arrow keys, respectively. You can jump by pressing the up arrow key. The player (represented by the red square) can jump on the goombas (represented by the brown squares). I used simple CSS styles for the visuals of the game. The collision detection between the player and goombas is checked every 100ms.
Note that this is a simplified example and not a full-fledged game. You can add more features, levels, etc. as per your requirements.