Sure! Here's a simple game featuring the Twirlywoos characters using JavaScript and HTML:
Twirlywoos Game
Click on the characters to score points!
Score: 0
In this game, there are four Twirlywoos characters: Great Bighoo, Toodloo, Chickedy and Chick. Each character has a different score. The player earns points by clicking on the characters. The score is displayed on the page, and it gets updated every time a character is clicked.
Remember to replace the image file names in the `<img>` tags with the actual names of the pictograms you'd like to use. Also, make sure to place the image files in the same directory as the HTML file for them to be displayed correctly.