Sure! Here's a simple tower defense game implemented as a single HTML file, using JavaScript and pictograms. Note that this is just a basic implementation and can be further enhanced:
Tower Defense Game
Money: $50
Click on a box to buy!
To play the game, you can simply copy and paste the above code into an HTML file, save it, and open the HTML file in any web browser. The game will start automatically, and you can click on the boxes to purchase them and prevent them from reaching the bottom of the screen. Enjoy!