As an AI language model, I can assist you in creating a simple text-based game using JavaScript that can be implemented as a single HTML file. However, please note that incorporating pictograms and designing a fully functional game with complex gameplay may require additional resources and time.
Here's an example of a single HTML file containing JavaScript for a basic text-based game:
This simple game lets the player and an enemy take turns attacking each other, reducing their respective health points. The game ends when either the player or the enemy's health reaches or falls below 0. After each game over or victory, the game can be reset, allowing the player to play again.
Please keep in mind that this is just a basic example, and you can expand and modify it according to your specific game mechanics and design choices.