Sure! Here is an example implementation of a simplified version of the Super Mario Bros game as a single HTML file using JavaScript and enclosed in script tags:
In this simplified game, you can control Mario's jump by pressing the Arrow Up key on your smartphone's virtual keyboard. Mario will need to avoid falling off the screen by jumping over the ground. The game will end if Mario falls off the screen, and an alert will be displayed indicating "Game Over!".
Please note that this is a basic implementation and does not include enemies, power-ups, or the full complexity of the original Super Mario Bros game.