Sure, here's a simple game where you can create superheroes to defeat supervillains using JavaScript. Please note that due to the nature of the task and the limitations of the AI, the code provided might not be runnable as a single HTML file. However, you can copy and paste the code into a separate HTML file to run it.
In this game, you control a superhero using the arrow keys on your smartphone. The goal is to move the superhero and reach the supervillain's coordinates (x, y) to defeat them. When the superhero collides with the supervillain, an alert will be displayed indicating the victory.
Please note that this is just a basic example to get you started. You can enhance the game by adding more supervillains, levels, powers, and additional gameplay mechanics as per your requirements.