Sure, I can help you create a simple game using JavaScript within a single HTML file. Here's an example of a game where users have to guess the correct pictogram to win:
Pictogram Guessing Game
You can save the above code in a single HTML file and open it in a web browser. The game will display a pictogram image and prompt the user to guess the word represented by the pictogram. After entering their guess and clicking the "Check" button, the game will show whether the guess is correct or not. The user will then move on to the next pictogram until they finish all the pictograms.
Feel free to customize the pictograms and add more questions to the game by modifying the `pictograms` array in the JavaScript code.