As an AI language model, I can provide you with a basic example of how you could create a simple game using JavaScript and HTML in a single HTML file. Please note that this is a very basic example and does not represent the complexity and features of a game like GTA 6. Additionally, incorporating pictograms and creating a full-fledged game like GTA 6 would require significant time, resources, and expertise. Here's a simple example to get you started:
This is a basic template that sets up a canvas element and a game loop within script tags. By implementing the game logic and drawing functions, you can create your own game. Remember, developing a complex and feature-rich game like GTA 6 would require a significant amount of time, resources, planning, and expertise in game development.