As an AI text-based model, I can provide you with a basic outline for creating a game called "Space Wars" using HTML, JavaScript, and pictograms. However, please note that creating a full-fledged game would require more time, effort, and expertise. Below is a simplified example to get you started:

1. HTML Setup:
Create an HTML file (e.g., index.html) and enclose the JavaScript code within the  tags. Use CSS and HTML to structure and stylize your game interface.

2. Pictograms:
Search for or create pictogram images to represent the spaceships, missiles, explosions, etc. Use these images to convey the game elements visually.

3. Game Logic:
a. Initialize game variables: 
   - Spaceship health
   - Player score
   - Enemy spaceship(s)
   - Missiles fired by player and enemies

b. Render the game screen:
   - Display spaceships, health bars, and score using pictograms and HTML elements.

c. Player Controls:
   - Implement touch or click events for player spaceship movement.
   - Handle touch or click events to fire missiles.

d. Enemy AI:
   - Create a function to control enemy spaceships' movements and missile firing.
   - Define their behavior, such as moving randomly, tracking the player, or evading missiles.

e. Collision Detection:
   - Detect collisions between player missiles and enemy spaceships.
   - Reduce enemy spaceship health or destroy them.
   - Update the player score.

f. Game Over:
   - Define a condition for game over, such as player spaceship health reaching zero.
   - Display a game over message and final score.
   - Optionally, add a button to restart the game.

4. Testing and Refining:
Test the game extensively, fix any bugs, and make adjustments to improve gameplay, graphics, and overall user experience.

Remember, creating a game can be a complex process, and the provided outline is just a starting point. You'll need to put in a lot of effort, creativity, and time to develop a fully functional and enjoyable game experience. Good luck!